Research focus
The overall aim of my research is to use single-nucleus sequencing and other molecular techniques to map the human hypothalamic functional architecture underlying appetitive control.
Background and experience
I completed my BSc in biological sciences with minors in genetics and biotechnology at North Carolina State University. I studied an obesity risk variant at the FAIM2 locus for my PhD in the Department of Genetics at the University of Pennsylvania’s Perelman School of Medicine. I’ve joined the IMS-MRL for postdoctoral training to expand my skillset and learn more about the genetics of obesity.
Working at the IMS-MRL
My current project involves using frozen human brain samples from donors with extreme bodyweights which are provided from the Cambridge Brain Bank. These samples will be used to transcriptionally profile hypothalamic cells using single-nucleus RNA-seq and map hypothalamic neural feeding circuitry using spatial transcriptomics. Together, these efforts will increase our understanding of the circuitry controlling food intake and modifying body weight in humans.
Awards
Recipient of a F31 Ruth L. Kirschstein Predoctoral Individual National Research Service Award from the National Institute of Child Health and Human Development 2022-2023
