Research focus
The overall aim of my research is to use investigate the molecular mechanisms of chemo- and mechano-sensitivity of enteroendocrine cells, using patch clamp, calcium imaging and secretion assays in human intestinal organoids.
Background and experience
I was born and raised in Chile, where I obtained my degree in Biology. Soon after that, I moved to the UK to join Oxford Brookes University’s Neuroscience PhD Program. Before joining the IMS, I did a postdoc at the Enteric Neuroscience program at Mayo Clinic, in the US.
I moved back to the UK and joined the Gribble-Reimann lab to learn about the use of CRSPR-Cas9 and human organoid in the study of enteroendocrine cells and their role as gut sensors.
Working at the IMS-MRL
My current project involves the study of ion channels and G-coupled protein receptors important for nutrient-sensing in human enteroendocrine cells.
Awards
Little Brain Big Brain (LBBB) 2018 – Best presentation award
American Neurogastroenterology and Motility Society- Young investigator award 2019
Little Brain Big Brain (LBBB) 2020 selected speaker and travel award.
