2024
| Risi R, Vidal-Puig AJ, Bidault G. An adipocentric perspective of pancreatic lipotoxicity in diabetes pathogenesis. J Endocrinol. 2024 Apr 1:JOE-23-0313. doi: 10.1530/JOE-23-0313. |
| Oussaada SM, Kilicarslan M, de Weijer BA, Gilijamse PW, Şekercan A, Virtue S, Janssen IMC, van de Laar A, Demirkiran A, van Wagensveld BA, Houdijk APJ, Jongejan A, Moerland PD, Verheij J, Geijtenbeek TB, Bloks VW, de Goffau MC, Romijn JA, Nieuwdorp M, Vidal-Puig A, Ter Horst KW, Serlie MJ. Tissue-specific inflammation and insulin sensitivity in subjects with obesity.Diabetes Res Clin Pract. 2024 Apr 12;211:111663. doi: 10.1016/j.diabres.2024.111663. |
| Tan J, Virtue S, Norris DM, Conway OJ, Yang M, Bidault G, Gribben C, Lugtu F, Kamzolas I, Krycer JR, Mills RJ, Liang L, Pereira C, Dale M, Shun-Shion AS, Baird HJ, Horscroft JA, Sowton AP, Ma M, Carobbio S, Petsalaki E, Murray AJ, Gershlick DC, Nathan JA, Hudson JE, Vallier L, Fisher-Wellman KH, Frezza C, Vidal-Puig A, Fazakerley DJ. EMBO J. 2024 Apr 5. doi: 10.1038/s44318-024-00084-7. |
| Ng MY, Song ZJ, Venkatesan G, Rodriguez-Cuenca S, West JA, Yang S, Tan CH, Ho PC, Griffin JL, Vidal-Puig A, Bassetto M, Hagen T. Conjugating uncoupler compounds with hydrophobic hydrocarbon chains to achieve adipose tissue selective drug accumulation.Sci Rep. 2024 Feb 28;14(1):4932. doi: 10.1038/s41598-024-54466-2. |
| Yu Y, Yang J, Zheng L, Su H, Cao S, Jiang X, Liu X, Liu W, Wang Z, Meng F, Xu H, Wen D, Sun C, Song X, Vidal-Puig A, Cao L. Dysfunction of Akt/FoxO3a/Atg7 regulatory loop magnifies obesity-regulated muscular mass decline. Mol Metab. 2024 Mar;81:101892. doi: 10.1016/j.molmet.2024.101892. |
| Li J, Fang J, Jiang X, Zhang Y, Vidal-Puig A, Zhang CY. RNAkines are secreted messengers shaping health and disease. Trends Endocrinol Metab. 2024 Mar;35(3):201-218. doi: 10.1016/j.tem.2023.12.004. |
| Lee E, Korf H, Vidal-Puig A. Reply to: "Liver-adipose tissue crosstalk in nonalcoholic fatty liver disease: the emerging role of remnant cholesterol": "BAT activation might improve NAFLD in patients, but this might require developing and/or maintaining functionally relevant levels of BAT mass." J Hepatol. 2024 Mar;80(3):e112-e114. doi: 10.1016/j.jhep.2023.10.027. |
| Golubic R, Kennet J, Parker V, Robertson D, Luo D, Hansen L, Jermutus L, Ambery P, Ryaboshapkina M, Surakala M, Laker RC, Venables M, Koulman A, Park A, Evans M. Dual glucagon-like peptide-1 and glucagon receptor agonism reduces energy intake in type 2 diabetes with obesity. Diabetes Obes Metab. 2024 Apr 1. doi: 10.1111/dom.15579. |
| Asowata EO, Romoli S, Sargeant R, Tan JY, Hoffmann S, Huang MM, Mahbubani KT, Krause FN, Jachimowicz D, Agren R, Koulman A, Jenkins B, Musial B, Griffin JL, Soderberg M, Ling S, Hansen PBL, Saeb-Parsy K, Woollard KJ. Multi-omics and imaging mass cytometry characterization of human kidneys to identify pathways and phenotypes associated with impaired kidney function. Kidney Int. 2024 Feb 29:S0085-2538(24)00168-6. doi: 10.1016/j.kint.2024.01.041. |
| Herrera-Marcos LV, Martínez-Beamonte R, Arnal C, Barranquero C, Puente-Lanzarote JJ, Lou-Bonafonte JM, Gonzalo-Romeo G, Mocciaro G, Jenkins B, Surra JC, Rodríguez-Yoldi MJ, Alastrué-Vera V, Letosa J, García-Gil A, Güemes A, Koulman A, Osada J. Lipidomic signatures discriminate subtle hepatic changes in the progression of porcine nonalcoholic steatohepatitis. Am J Physiol Gastrointest Liver Physiol. 2024 Apr 1;326(4):G411-G425. doi: 10.1152/ajpgi.00264.2023. |
| Olga L, McKenzie K, Kerac M, Boyne M, Badaloo A, Bandsma RHJ, Koulman A, Thompson DS. Weight gain during nutritional rehabilitation post-childhood malnutrition may influence the associations between adulthood desaturases activity and anthro-cardiometabolic risk factors. Clin Nutr. 2024 Mar;43(3):747-755. doi: 10.1016/j.clnu.2024.01.032. |
| Kincaid JWR, Rimmington D, Tadross JA, Cimino I, Zvetkova I, Kaser A, Richards P, Patel S, O'Rahilly S, Coll AP. The gastrointestinal tract is a major source of the acute metformin-stimulated rise in GDF15. Sci Rep. 2024 Jan 22;14(1):1899. doi: 10.1038/s41598-024-51866-2. |
| Fejzo M, Rocha N, Cimino I, Lockhart SM, Petry CJ, Kay RG, Burling K, Barker P, George AL, Yasara N, Premawardhena A, Gong S, Cook E, Rimmington D, Rainbow K, Withers DJ, Cortessis V, Mullin PM, MacGibbon KW, Jin E, Kam A, Campbell A, Polasek O, Tzoneva G, Gribble FM, Yeo GSH, Lam BYH, Saudek V, Hughes IA, Ong KK, Perry JRB, Sutton Cole A, Baumgarten M, Welsh P, Sattar N, Smith GCS, Charnock-Jones DS, Coll AP, Meek CL, Mettananda S, Hayward C, Mancuso N, O'Rahilly S. GDF15 linked to maternal risk of nausea and vomiting during pregnancy. Nature. 2024 Jan;625(7996):760-767. doi: 10.1038/s41586-023-06921-9. |
| Buller S, Blouet C. Brain access of incretins and incretin receptor agonists to their central targets relevant for appetite suppression and weight loss. Am J Physiol Endocrinol Metab. 2024 Apr 1;326(4):E472-E480. doi: 10.1152/ajpendo.00250.2023. |
| Azhar M, Watson LPE, De Lucia Rolfe E, Ferraro M, Carr K, Worsley J, Boesch C, Hodson L, Chatterjee KK, Kemp GJ, Savage DB, Sleigh A. Association of insulin resistance with the accumulation of saturated intramyocellular lipid: A comparison with other fat stores. NMR Biomed. 2024 Feb 14:e5117. doi: 10.1002/nbm.5117. |
| Enríquez-Schmidt J, Mautner Molina C, Kalazich Rosales M, Muñoz M, Ruiz-Uribe M, Fuentes Leal F, Monrroy Uarac M, Cárcamo Ibaceta C, Fazakerley DJ, Larance M, Ehrenfeld P, Martínez-Huenchullán S. Moderate-intensity constant or high-intensity interval training? Metabolic effects on candidates to undergo bariatric surgery. Nutr Metab Cardiovasc Dis. 2024 Mar 5:S0939-4753(24)00087-5. doi: 10.1016/j.numecd.2024.03.001. |
| Zhao Y, Chukanova M, Kentistou KA, Fairhurst-Hunter Z, Siegert AM, Jia RY, Dowsett GKC, Gardner EJ, Lawler K, Day FR, Kaisinger LR, Tung YL, Lam BYH, Chen HC, Wang Q, Berumen-Campos J, Kuri-Morales P, Tapia-Conyer R, Alegre-Diaz J, Barroso I, Emberson J, Torres JM, Collins R, Saleheen D, Smith KR, Paul DS, Merkle F, Farooqi IS, Wareham NJ, Petrovski S, O'Rahilly S, Ong KK, Yeo GSH, Perry JRB. Protein-truncating variants in BSN are associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease. Nat Genet. 2024 Apr;56(4):579-584. doi: 10.1038/s41588-024-01694-x. |
| Ryan M, McDonough JA, Ward ME, Cookson MR, Skarnes WC, Merkle FT. Large structural variants in KOLF2.1J are unlikely to compromise neurological disease modeling. Cell Stem Cell. 2024 Mar 7;31(3):290-291. doi: 10.1016/j.stem.2024.02.006. |
| Ryan M, McDonough JA, Ward ME, Cookson MR, Skarnes WC, Merkle FT. Large structural variants in KOLF2.1J are unlikely to compromise neurological disease modelling. bioRxiv [Preprint]. 2024 Jan 29:2024.01.29.577739. doi: 10.1101/2024.01.29.577739. |
| Jörgensen SK, Karnošová A, Mazzaferro S, Rowley O, Chen HC, Robbins SJ, Christofides S, Merkle FT, Maletínská L, Petrik D. An analogue of the Prolactin Releasing Peptide reduces obesity and promotes adult neurogenesis. EMBO Rep. 2024 Jan;25(1):351-377. doi: 10.1038/s44319-023-00016-2. |
| Lewis JE, Nuzzaci D, James-Okoro PP, Montaner M, O'Flaherty Rottenberger E, Darwish T, Hayashi M, Liberles SD, Hornigold D, Naylor J, Baker D, Gribble FM, Reimann F. Stimulating intestinal GIP release reduces food intake and body weight in mice. Mol Metab. 2024 Apr 21:101945. doi: 10.1016/j.molmet.2024.101945. |
| Foreman RE, Bannon CA, Kay RG, Reimann F, Gribble FM. Motilin fluctuations in healthy volunteers determined by liquid chromatography mass spectrometry. Front Endocrinol (Lausanne). 2024 Mar 13;15:1348146. doi: 10.3389/fendo.2024.1348146. |
| Bannon CA, Meek CL, Reimann F, Gribble FM. Fasting and post prandial pancreatic and enteroendocrine hormone levels in obese and non-obese participants. Peptides. 2024 Mar 13;176:171186. doi: 10.1016/j.peptides.2024.171186. |
| Santos-Hernández M, Reimann F, Gribble FM. Cellular mechanisms of incretin hormone secretion. J Mol Endocrinol. 2024 Feb 22;72(4):e230112. doi: 10.1530/JME-23-0112. |
| Leeson-Payne A, Iyinikkel J, Malcolm C, Lam BYH, Sommer N, Dowsett GKC, Martinez de Morentin PB, Thompson D, Mackenzie A, Chianese R, Kentistou K, Gardner EJ, Perry JRB, Grassmann F, Speakman JR, Rochford JJ, Yeo GSH, Murray F, Heisler LK. Loss of GPR75 protects against non-alcoholic fatty liver disease and body fat accumulation. Cell Metab. 2024 Apr 18:S1550-4131(24)00120-7. doi: 10.1016/j.cmet.2024.03.016. |
| Kühnen P, Argente J, Clément K, Dollfus H, Dubern B, Farooqi S, de Groot C, Grüters A, Holm JC, Hopkins M, Kleinendorst L, Körner A, Meeker D, Rydén M, von Schnurbein J, Tschöp M, Yeo GSH, Zorn S, Wabitsch M. IMPROVE 2022 International Meeting on Pathway-Related Obesity: Vision of Excellence. Clin Obes. 2024 Apr 11:e12659. doi: 10.1111/cob.12659. |
| Martinez de Morentin PB, Gonzalez JA, Dowsett GKC, Martynova Y, Yeo GSH, Sylantyev S, Heisler LK. A brainstem to hypothalamic arcuate nucleus GABAergic circuit drives feeding. Curr Biol. 2024 Apr 22;34(8):1646-1656.e4. doi: 10.1016/j.cub.2024.02.074. |
| Dittmann MT, Lakatos G, Wainwright JF, Mokrosinski J, Cross E, Farooqi IS, Wallis NJ, Halsey LG, Wilson R, O'Rahilly S, Yeo GSH, Raffan E. Low resting metabolic rate and increased hunger due to β-MSH and β-endorphin deletion in a canine model. Sci Adv. 2024 Mar 8;10(10):eadj3823. doi: 10.1126/sciadv.adj3823. |
| Pietzner M, Uluvar B, Kolnes KJ, Jeppesen PB, Frivold SV, Skattebo Ø, Johansen EI, Skålhegg BS, Wojtaszewski JFP, Kolnes AJ, Yeo GSH, O'Rahilly S, Jensen J, Langenberg C. Systemic proteome adaptions to 7-day complete caloric restriction in humans. Nat Metab. 2024 Mar 1. doi: 10.1038/s42255-024-01008-9. |
| von Schnurbein J, Zorn S, Nunziata A, Brandt S, Moepps B, Funcke JB, Hussain K, Farooqi IS, Fischer-Posovszky P, Wabitsch M. Classification of Congenital Leptin Deficiency. J Clin Endocrinol Metab. 2024 Mar 12:dgae149. doi: 10.1210/clinem/dgae149. |
| Kentistou KA, Lim BEM, Kaisinger LR, Steinthorsdottir V, Sharp LN, Patel KA, Tragante V, Hawkes G, Gardner EJ, Olafsdottir T, Wood AR, Zhao Y, Thorleifsson G, Day FR, Ozanne SE, Hattersley AT, O'Rahilly S, Stefansson K, Ong KK, Beaumont RN, Perry JRB, Freathy RM. Rare variant associations with birth weight identify genes involved in adipose tissue regulation, placental function and insulin-like growth factor signalling. medRxiv [Preprint]. 2024 Apr 3:2024.04.03.24305248. doi: 10.1101/2024.04.03.24305248. |
| Adams DJ, Barlas B, McIntyre RE, Salguero I, van der Weyden L, Barros A, Vicente JR, Karimpour N, Haider A, Ranzani M, Turner G, Thompson NA, Harle V, Olvera-León R, Robles-Espinoza CD, Speak AO, Geisler N, Weninger WJ, Geyer SH, Hewinson J, Karp NA; Sanger Mouse Genetics Project; Fu B, Yang F, Kozik Z, Choudhary J, Yu L, van Ruiten MS, Rowland BD, Lelliott CJ, Del Castillo Velasco-Herrera M, Verstraten R, Bruckner L, Henssen AG, Rooimans MA, de Lange J, Mohun TJ, Arends MJ, Kentistou KA, Coelho PA, Zhao Y, Zecchini H, Perry JRB, Jackson SP, Balmus G. Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136. doi: 10.1038/s41586-023-07009-0. |
| Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes. Bradfield JP, Kember RL, Ulrich A, Balkiyarova Z, Alyass A, Aris IM, Bell JA, Broadaway KA, Chen Z, Chai JF, Davies NM, Fernandez-Orth D, Bustamante M, Fore R, Ganguli A, Heiskala A, Hottenga JJ, Íñiguez C, Kobes S, Leinonen J, Lowry E, Lyytikainen LP, Mahajan A, Pitkänen N, Schnurr TM, Have CT, Strachan DP, Thiering E, Vogelezang S, Wade KH, Wang CA, Wong A, Holm LA, Chesi A, Choong C, Cruz M, Elliott P, Franks S, Frithioff-Bøjsøe C, Gauderman WJ, Glessner JT, Gilsanz V, Griesman K, Hanson RL, Kaakinen M, Kalkwarf H, Kelly A, Kindler J, Kähönen M, Lanca C, Lappe J, Lee NR, McCormack S, Mentch FD, Mitchell JA, Mononen N, Niinikoski H, Oken E, Pahkala K, Sim X, Teo YY, Baier LJ, van Beijsterveldt T, Adair LS, Boomsma DI, de Geus E, Guxens M, Eriksson JG, Felix JF, Gilliland FD, Biobank PM, Hansen T, Hardy R, Hivert MF, Holm JC, Jaddoe VWV, Järvelin MR, Lehtimäki T, Mackey DA, Meyre D, Mohlke KL, Mykkänen J, Oberfield S, Pennell CE, Perry JRB et al. Genome Biol. 2024 Jan 16;25(1):22. doi: 10.1186/s13059-023-03136-z. |
| Yazdanpanah N, Jumentier B, Yazdanpanah M, Ong KK, Perry JRB, Manousaki D. Mendelian randomization identifies circulating proteins as biomarkers for age at menarche and age at natural menopause. Commun Biol. 2024 Jan 6;7(1):47. doi: 10.1038/s42003-023-05737-7. |
| Anderson GM, Hill JW, Kaiser UB, Navarro VM, Ong KK, Perry JRB, Prevot V, Tena-Sempere M, Elias CF. Metabolic control of puberty: 60 years in the footsteps of Kennedy and Mitra's seminal work. Nat Rev Endocrinol. 2024 Feb;20(2):111-123. doi: 10.1038/s41574-023-00919-z. |
| Chondronikola M, Yoshino J, Ramaswamy R, Giardina JD, Laforest R, Wahl RL, Patterson BW, Mittendorfer B, Klein S. Very-low-density lipoprotein triglyceride and free fatty acid plasma kinetics in women with high or low brown adipose tissue volume and overweight/obesity. Cell Rep Med. 2024 Jan 16;5(1):101370. doi: 10.1016/j.xcrm.2023.101370. |
| Haberbosch L, MacFarlane J, Koulouri O, Gillett D, Powlson AS, Oddy S, Halsall DJ, Huynh KA, Jones J, Cheow HK, Spranger J, Mai K, Strasburger CJ, Mannion RJ, Gurnell M. Real-world experience with 11C-methionine positron emission tomography in the management of acromegaly. Eur J Endocrinol. 2024 Mar 30;190(4):307-313. doi: 10.1093/ejendo/lvae028. |
| Ersche KD, Stochl J, Brühl AB, Gurnell M. Evidence of Hypothalamic-Pituitary-Adrenal and -Gonadal Dysfunction in Cocaine-Addicted Men. Eur Addict Res. 2024;30(2):114-120. doi: 10.1159/000535584. |
| Powlson AS, Annamalai AK, Moir S, Webb AJ, Bala L, Graggaber J, Kandasamy N, Koulouri O, Halsall DJ, Shneerson JM, Gurnell M. High prevalence of severe sleep cycle disruption in de novo acromegaly and underdiagnosis by common clinical screening tools: A prospective, observational, cross-sectional study. Clin Endocrinol (Oxf). 2024 Mar;100(3):251-259. doi: 10.1111/cen.14994. |
| Hird M, Russell JJ, Corrigan LL, Boros I, Nordeman P, Antoni G, Gurnell M, Aigbirhio FI. Automated radiosynthesis of [18 F]CETO, a PET radiotracer for imaging adrenal glands, on Synthra Rnplus. J Labelled Comp Radiopharm. 2024 Feb;67(2):67-75. doi: 10.1002/jlcr.4078. |
| Gurnell M, Radwan A, Bachert C, Lugogo N, Cho SH, Nash S, Zhang H, Khan AH, Jacob-Nara JA, Rowe PJ, Deniz Y. Dupilumab Reduces Asthma Disease Burden and Recurrent SCS Use in Patients with CRSwNP and Coexisting Asthma. J Asthma Allergy. 2024 Jan 16;17:1-8. doi: 10.2147/JAA.S420140. |
| Moran C, Schoenmakers N, Halsall D, Oddy S, Lyons G, van den Berg S, Gurnell M, Chatterjee K. Approach to the Patient With Raised Thyroid Hormones and Nonsuppressed TSH. J Clin Endocrinol Metab. 2024 Mar 15;109(4):1094-1108. doi: 10.1210/clinem/dgad681. |
| Arginine or Hypertonic Saline-Stimulated Copeptin to Diagnose AVP Deficiency. Petersenn S, Fleseriu M, Casanueva FF, Giustina A, Biermasz N, Biller BMK, Bronstein M, Chanson P, Fukuoka H, Gadelha M, Greenman Y, Gurnell M, Ho KKY, Honegger J, Ioachimescu AG, Kaiser UB, Karavitaki N, Katznelson L, Lodish M, Maiter D, Marcus HJ, McCormack A, Molitch M, Muir CA, Neggers S, Pereira AM, Pivonello R, Post K, Raverot G, Salvatori R, Samson SL, Shimon I, Spencer-Segal J, Vila G, Wass J, Melmed S. Nat Rev Endocrinol. 2024 Jan;20(1):62. doi: 10.1038/s41574-023-00916-2. |
| Kadiyala N, Wilinska ME, Daly AB, Nwokolo M, Lakshman R, Hartnell S, Ware J, Allen JM, Cezar A, Evans ML, Hovorka R, Boughton CK. Hypoglycemia and Hyperglycemia According to Type of Diabetes: Observations During Fully Closed-Loop Insulin Delivery in Adults With Type 1 and Type 2 Diabetes. J Diabetes Sci Technol. 2024 Apr 13:19322968241242803. doi: 10.1177/19322968241242803. |
| The INNODIA Type 1 Diabetes Natural History Study: a Marcovecchio ML, Hendriks AEJ, Delfin C, Battelino T, Danne T, Evans ML, Johannesen J, Kaur S, Knip M, Overbergh L, Pociot F, Todd JA, Van der Schueren B, Wicker LS, Peakman M, Mathieu C; INNODIA consortium. European cohort of newly diagnosed children, adolescents and adults. Diabetologia. 2024 Mar 22. doi: 10.1007/s00125-024-06124-5. |
| Lakshman R, Hartnell S, Ware J, Allen JM, Wilinska ME, Nwokolo M, Evans ML, Hovorka R, Boughton CK. Lived Experience of Fully Closed-Loop Insulin Delivery in Adults with Type 1 Diabetes. Diabetes Technol Ther. 2024 Apr;26(4):211-221. doi: 10.1089/dia.2023.0394. |
| Counterregulatory hormone and symptom responses to hypoglycaemia in people with type 1 diabetes, insulin-treated type 2 diabetes or without diabetes: the Hypo-RESOLVE hypoglycaemic clamp study. Fabricius TW, Verhulst CEM, Kristensen PL, Holst JJ, Tack CJ, McCrimmon RJ, Heller SR, Evans ML, de Galan BE, Pedersen-Bjergaard U; Hypo-RESOLVE consortium. Counterregulatory hormone and symptom responses to hypoglycaemia in people with type 1 diabetes, insulin-treated type 2 diabetes or without diabetes: the Hypo-RESOLVE hypoglycaemic clamp study. Acta Diabetol. 2024 Feb 20. doi: 10.1007/s00592-024-02239-8. |
| Haliloglu B, Boughton CK, Lakshman R, Ware J, Nwokolo M, Thabit H, Mader JK, Bally L, Leelarathna L, Wilinska ME, Allen JM, Hartnell S, Evans ML, Hovorka R. Postprandial Glucose Excursions with Ultra-Rapid Insulin Analogs in Hybrid Closed-Loop Therapy for Adults with Type 1 Diabetes. Diabetes Technol Ther. 2024 Feb 27. doi: 10.1089/dia.2023.0509. |
| Leelarathna L, Sutton CJ, Evans ML, Neupane S, Rayman G, Lumley S, Cranston I, Narendran P, Krishan A, Taxiarchi VP, Barnard-Kelly K, Elliott RA, Burns M, Camm M, Thabit H, Wilmot EG; FLASH-UK Trial Study Group. Intermittently scanned continuous glucose monitoring in adults with type 1 diabetes: A subgroup analysis from the FLASH-UK study. Diabet Med. 2024 Mar;41(3):e15249. doi: 10.1111/dme.15249. |
| MacGloin H, Schoenmakers N, Moorwood C, Buchanan CR, Arya VB. Congenital Central Hypothyroidism Caused by Novel Variants in IGSF1 Gene : Case Series of three patients. Horm Res Paediatr. 2024 Jan 31. doi: 10.1159/000536385. |
| Aman LCS, Lester SD, Holland AJ, Fletcher PC.Psychotic illness in people with Prader-Willi syndrome: a systematic review of clinical presentation, course and phenomenology. Orphanet J Rare Dis. 2024 Feb 15;19(1):69. doi: 10.1186/s13023-024-03026-y. |
| Wolpe N, Holton R, Fletcher PC. What Is Mental Effort: A Clinical Perspective Biol Psychiatry. 2024 Feb 1:S0006-3223(24)00065-9. doi: 10.1016/j.biopsych.2024.01.022. |
| Daniel-Watanabe L, Fletcher PC. Reply to: In Search of the Behavioral and Neural Basis for Differentiating Fear and Anxiety. Biol Psychiatry Glob Open Sci. 2023 Jul 23;4(1):396-397. doi: 10.1016/j.bpsgos.2023.07.003. |
| Harding JN, Wolpe N, Brugger SP, Navarro V, Teufel C, Fletcher PC. A new predictive coding model for a more comprehensive account of delusions. Lancet Psychiatry. 2024 Apr;11(4):295-302. doi: 10.1016/S2215-0366(23)00411-X. |
| Clay F, Hunt R, Obiefuna N, Solly JE, Watson E, Wilkinson A, Chohan R, Hatfield C, Fletcher PC, Underwood BR. The Use of Immersive Virtual Reality in Sensory Sessions on a Specialist Dementia Unit: Service Evaluation of Feasibility and Acceptability. Occup Ther Health Care. 2024 Apr;38(2):317-330. doi: 10.1080/07380577.2023.2270052. |
| Lakshman R, Najami M, Hovorka R, Boughton CK. Contrasting Glycemic Outcomes in Young People with Diabetic Ketoacidosis at Onset of Type 1 Diabetes. Diabetes Technol Ther. 2024 Apr 16. doi: 10.1089/dia.2024.0147. |
| Fox DS, Ware J, Boughton CK, Allen JM, Wilinska ME, Tauschmann M, Denvir L, Thankamony A, Campbell F, Wadwa RP, Buckingham BA, Davis N, DiMeglio LA, Mauras N, Besser REJ, Ghatak A, Weinzimer SA, Kanapka L, Kollman C, Sibayan J, Beck RW, Hood KK, Hovorka R. Cost-Effectiveness of Closed-Loop Automated Insulin Delivery Using the Cambridge Hybrid Algorithm in Children and Adolescents with Type 1 Diabetes: Results from a Multicenter 6-Month Randomized Trial. J Diabetes Sci Technol. 2024 Mar 17:19322968241231950. doi: 10.1177/19322968241231950. |
| Lakshman R, Najami M, Allen JM, Ware J, Wilinska ME, Hartnell S, Thankamony A, Randell T, Ghatak A, Besser REJ, Elleri D, Trevelyan N, Campbell FM, Hovorka R, Boughton CK. Diabetic Ketoacidosis at Onset of Type 1 Diabetes and Glycemic Outcomes with Closed-Loop Insulin Delivery. Diabetes Technol Ther. 2024 Mar;26(3):198-202. doi: 10.1089/dia.2023.0307. |
| Thabit H, Boughton C, Mubita W, Rubio J, Allen S, Heugh R, Mader JK, Narendran P, Evans M, Leelarathna L, Wilinska ME, Fullwood C, Garratt C, Hovorka R, Rutter MK. Impact of hybrid closed-loop insulin delivery on cardiac rhythm in older adults with type 1 diabetes: A post hoc analysis of trial data. Diabetes Obes Metab. 2024 Mar;26(3):1105-1109. doi: 10.1111/dom.15366. |
| Takele WW, Vesco KK, Josefson J, Redman LM, Hannah W, Bonham MP, Chen M, Chivers SC, Fawcett AJ, Grieger JA, Habibi N, Leung GKW, Liu K, Mekonnen EG, Pathirana M, Quinteros A, Taylor R, Ukke GG, Zhou SJ; ADA/EASD PMDI; Lim S. Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis. Commun Med (Lond). 2024 Apr 20;4(1):75. doi: 10.1038/s43856-024-00491-1. |
| Felton JL, Redondo MJ, Oram RA, Speake C, Long SA, Onengut-Gumuscu S, Rich SS, Monaco GSF, Harris-Kawano A, Perez D, Saeed Z, Hoag B, Jain R, Evans-Molina C, DiMeglio LA, Ismail HM, Dabelea D, Johnson RK, Urazbayeva M, Wentworth JM, Griffin KJ, Sims EK; ADA/EASD PMDI. Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review. Commun Med (Lond). 2024 Apr 6;4(1):66. doi: 10.1038/s43856-024-00478-y. |
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2022
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2021
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| Olga L, van Diepen JA, Bobeldijk-Pastorova I, Gross G, Prentice PM, Snowden SG, Furse S, Kooistra T, Hughes IA, Schoemaker MH, van Tol EAF, van Duyvenvoorde W, Wielinga PY, Ong KK, Dunger DB, Kleemann R, Koulman A. Lipid ratios representing SCD1, FADS1, and FADS2 activities as candidate biomarkers of early growth and adiposity. EBioMedicine. 2021 Jan 6;63:103198. doi: 10.1016/j.ebiom.2020.103198. Epub ahead of print. PMID: 33421943; PMCID: PMC7806876. |
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| Alvarez-Guaita A, Patel S, Lim K, Haider A, Dong L, Conway OJ, Ma MKL, Chiarugi D, Saudek V, O'Rahilly S, Savage DB. Phenotypic characterisation of Adig null mice suggests roles for adipogenin in the regulation of fat mass accrual and leptin secretion. Cell Reports. 2021 Mar 9;34(10):108810. doi: 10.1016/j.celrep.2021.108810. |
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| O'Rahilly S.. "Treasure Your Exceptions"-Studying Human Extreme Phenotypes to Illuminate Metabolic Health and Disease: The 2019 Banting Medal for Scientific Achievement Lecture. Diabetes. 2021 Jan;70(1):29-38. doi: 10.2337/dbi19-0037. |
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2019
| Roberts GP, Larraufie P, Richards P, Kay RG, Galvin SG, Miedzybrodzka EL, Leiter A, Li HJ, Glass LL, Ma MKL, Lam B, Yeo GSH, Scharfmann R, Chiarugi D, Hardwick RH, Reimann F, Gribble FM. Comparison of Human and Murine Enteroendocrine Cells by Transcriptomic and Peptidomic Profiling. Diabetes. 2019 May;68(5):1062-1072. doi: 10.2337/db18-0883. Epub 2019 Feb 7. PubMed PMID: 30733330; PubMed Central PMCID: PMC6477899. |
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| Ruan Y, Willemsen RH, Wilinska ME, Tauschmann M, Dunger DB, Hovorka R. Mixed-meal tolerance test to assess residual beta-cell secretion: Beyond the area-under-curve of plasma C-peptide concentration. Pediatr Diabetes. 2019 May;20(3):282-285. doi: 0.1111/pedi.12816. Epub 2019 Feb 19. PubMed PMID: 30652426; PubMed Central PMCID: PMC6487945. |
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| Sefton C, Davies A, Allen TJ, Wray JR, Shoop R, Adamson A, Humphreys N, Coll AP, White A, Harno E. Metabolic Abnormalities of Chronic High-Dose Glucocorticoids Are Not Mediated by Hypothalamic AgRP in Male Mice. Endocrinology. 2019 May 1;160(5):964-978. doi: 10.1210/en.2019-00018. PubMed PMID: 30794724; PubMed Central PMCID: PMC6444294. |
| Lotta LA, Mokrosiński J, Mendes de Oliveira E, Li C, Sharp SJ, Luan J, Brouwers B, Ayinampudi V, Bowker N, Kerrison N, Kaimakis V, Hoult D, Stewart ID, Wheeler E, Day FR, Perry JRB, Langenberg C, Wareham NJ, Farooqi IS. Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity. Cell. 2019 Apr 18;177(3):597-607.e9. doi: 10.1016/j.cell.2019.03.044. PubMed PMID: 31002796; PubMed Central PMCID: PMC6476272. |
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| Boughton CK, Hovorka R. Advances in artificial pancreas systems. Sci Transl Med. 2019 Mar 20;11(484). pii: eaaw4949. doi: 10.1126/scitranslmed.aaw4949. Review. PubMed PMID: 30894501. |
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| Schierloh U, Wilinska ME, Pit-Ten Cate IM, Baumann P, Hovorka R, De Beaufort C; Spidiman Study Group: Single Port Insulin Infusion for Improved Diabetes Management. Lower plasma insulin levels during overnight closed-loop in school children with type 1 diabetes: Potential advantage? A randomized cross-over trial. PLoS One. 2019 Mar 8;14(3):e0212013. doi: 10.1371/journal.pone.0212013. eCollection 2019. PubMed PMID: 30849076; PubMed Central PMCID: PMC6408001. |
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| O'Shea PM, O'Donoghue D, Bashari W, Senanayake R, Joyce MB, Powlson AS, Browne D, O'Sullivan GJ, Cheow H, Mendichovszky I, Quill D, Lowery A, Lappin D, Gurnell M, Dennedy MC. (11) C-Metomidate PET/CT is a useful adjunct for lateralization of primary aldosteronism in routine clinical practice. Clin Endocrinol (Oxf). 2019 May;90(5):670-679. doi: 10.1111/cen.13942. Epub 2019 Mar 18. PubMed PMID: 30721535. |
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| Gribble FM, Reimann F. Function and mechanisms of enteroendocrine cells and gut hormones in metabolism. Nat Rev Endocrinol. 2019 Apr;15(4):226-237. doi: 10.1038/s41574-019-0168-8. Review. PubMed PMID: 30760847. |
| Larraufie P, Roberts GP, McGavigan AK, Kay RG, Li J, Leiter A, Melvin A, Biggs EK, Ravn P, Davy K, Hornigold DC, Yeo GSH, Hardwick RH, Reimann F, Gribble FM. Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery. Cell Rep. 2019 Feb 5;26(6):1399-1408.e6. doi: 10.1016/j.celrep.2019.01.047. PubMed PMID: 30726726; PubMed Central PMCID: PMC6367566. |
| Lu VB, Rievaj J, O'Flaherty EA, Smith CA, Pais R, Pattison LA, Tolhurst G, Leiter AB, Bulmer DC, Gribble FM, Reimann F. Adenosine triphosphate is co-secreted with glucagon-like peptide-1 to modulate intestinal enterocytes and afferent neurons. Nat Commun. 2019 Mar 4;10(1):1029. doi: 10.1038/s41467-019-09045-9. PubMed PMID: 30833673; PubMed Central PMCID: PMC6399286. |
| Vergari E, Knudsen JG, Ramracheya R, Salehi A, Zhang Q, Adam J, Asterholm IW, Benrick A, Briant LJB, Chibalina MV, Gribble FM, Hamilton A, Hastoy B, Reimann F, Rorsman NJG, Spiliotis II, Tarasov A, Wu Y, Ashcroft FM, Rorsman P. Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion. Nat Commun. 2019 Jan 11;10(1):139. doi: 10.1038/s41467-018-08193-8. PubMed PMID: 30635569; PubMed Central PMCID: PMC6329806. |
| Vestergaard ET, Hjelholt AJ, Kuhre RE, Møller N, Larraufie P, Gribble FM, Reimann F, Jessen N, Holst JJ, Jørgensen JOL. Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients. J Clin Endocrinol Metab. 2019 Jul 1;104(7):2581-2592. doi: 10.1210/jc.2018-02503. PubMed PMID: 30726969. |
| Rudenko O, Shang J, Munk A, Ekberg JP, Petersen N, Engelstoft MS, Egerod KL, Hjorth SA, Wu M, Feng Y, Zhou YP, Mokrosinski J, Thams P, Reimann F, Gribble F, Rehfeld JF, Holst JJ, Treebak JT, Howard AD, Schwartz TW. The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones. Mol Metab. 2019 Jan;19:49-64. doi: 10.1016/j.molmet.2018.10.012. Epub 2018 Nov 5. PubMed PMID: 30472415; PubMed Central PMCID: PMC6323244. |
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| Patel V, Bidault G, Chambers JE, Carobbio S, Everden AJT, Garcés C, Dalton LE, Gribble FM, Vidal-Puig A, Marciniak SJ. Inactivation of Ppp1r15a minimises weight gain and insulin resistance during caloric excess in female mice. Sci Rep. 2019 Feb 27;9(1):2903. doi: 10.1038/s41598-019-39562-y. PubMed PMID: 30814564; PubMed Central PMCID: PMC6393541. |
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| Riveros-McKay F, Mistry V, Bounds R, Hendricks A, Keogh JM, Thomas H, Henning E, Corbin LJ; Understanding Society Scientific Group, O'Rahilly S, Zeggini E, Wheeler E, Barroso I, Farooqi IS. Genetic architecture of human thinness compared to severe obesity. PLoS Genet. 2019 Jan 24;15(1):e1007603. doi: 10.1371/journal.pgen.1007603. eCollection 2019 Jan. PubMed PMID: 30677029; PubMed Central PMCID: PMC6345421. |
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