The Institute of Metabolic Science- Metabolic Research Laboratories (IMS-MRL) brings together outstanding scientific and clinical researchers to form an international centre of excellence for research into metabolism and metabolic disease.
The IMS-MRL and its embedded Medical Research Council (MRC) Metabolic Diseases Unit investigate the mechanisms through which metabolic health is maintained and how this is disturbed in disease. We seek to use that knowledge to aid better treatment and prevention of obesity, Type 2 diabetes and related endocrine and metabolic diseases.
IMS-MRL groups encompass skills in genetics, cell biology, cell signalling, neuroendocrinology, bioenergetics, human and animal physiology, experimental medicine and clinical trials.
Latest news
Congratulations to Professor Sue Ozanne - New Director and Head of Department
8 October 2024
The IMS-MRL is delighted to announce that Professor Susan Ozanne PhD FMedSci has recently been appointed as its new Director. Sue will also take on the roles of Co-Director of the IMS and Head of the University Department of Clinical Biochemistry. Professor Stephen O’Rahilly MD FRS FMedSci will remain Director of the MRC...
25 September 2024
A study led by Sam Lockhart, Milan Muso , Steve O’Rahilly and others at the IMS-MRL, working with collaborators at the Universities of California, Newcastle and Leicester, has discovered that having some fat (specifically, a type of fat known as triglyceride) in liver cells may help the liver from being seriously damaged...
MicroRNA-483: a missing link between the major growth factors IGF2 and IGF1
23 September 2024
Researchers from the Constancia group led by Ionel Sandovici and Denise Fernandez-Twinn, the Ozanne group and many other colleagues at the IMS-MRL, working in collaboration with the Universities of Cambridge, Glasgow, Montreal and Vienna, have unravelled a previously unrecognized link between Insulin-like growth factor 1 (...
